Application

For use in histochemical staining of b-galactosidase actifvity.

Biochem/physiol Actions

Replicative senescence is a growth-arrest state associated with loss of division potential, changes in cell morphology, shape and physical appearance, and the pattern of gene expression in cells.

General description

The Senescence Cells Histochemical Staining Kit contains all the reagents required for identifying senescent cells using an assay based on a histochemical stain for -galactosidase activity at pH 6. -galactosidase activity is detectable in senescent cells, but not in quiescent, immortal, or tumor cells.

Legal Information

Manufactured under license to US Patent Nos. 5,491,069 and 5,795,728.